This testing is recommended for families with a high risk of a genetic predisposition to certain cancers such as breast cancer. A predisposition to breast cancer can be inherited via altered genes. Genetic testing aims to detect a genetic alteration, through their blood or tissue samples, that might increase the chances of a person developing a breast cancer. BRCA-1 and BRCA-2 are the two genes associated to hereditary breast cancer. 

Generally, it is necessary to test the women who has had breast cancer first to identify the genetic change causing cancer in the family. Blood relatives who have no signs of breast cancer can then choose to have testing to find out if they have inherited the altered genes that may make it more likely for them to get breast cancer.

TrueTM Hereditary Cancer Tests:

• Easy to interpret and clinically actionable results
• Blood or saliva accepted

BreastTrueTM High Risk Panel:

• Comprehensive analysis of 7 high-risk breast cancer genes including PALB2
• Average turnaround time of 3 weeks

BRCATrueTM:

• Comprehensive analysis of BRCA1 and BRCA2
• Average turnaround time of 2 weeks

BRCATrueTM Ashkenazi Jewish (3-Site):

• Analysis of the 3 common Ashkenazi Jewish mutations
• Average turnaround time of 2 weeks

BRCATrueTM Hispanic (8-Site):

• Analysis of 8 recurrent pathogenic variants in the Mexican and Hispanic populations
• Average turnaround time of 2 weeks

Available Reflex Options:

• BRCATrue™ Ashkenazi Jewish (3-site) with reflex toBRCATrue™
• BRCATrue™ Ashkenazi Jewish (3-site) with reflex to BreastTrue High Risk Panel
• BRCATrue™ Hispanic (8-site) with reflex toBRCATrue™
• BRCATrue™ Hispanic Jewish (8-site) with reflex to BreastTrue High Risk Panel
• BRCATrue™ with reflex to BreastTrue High Risk Panel

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